4 edition of Broadening the spectrum of clinical uses of antiepileptic drugs found in the catalog.
Includes bibliographical references and index.
|Statement||edited by J. M. Pellock.|
|Series||International Congress and Symposium series,, 241|
|Contributions||Pellock, John M.|
|LC Classifications||RM322 .B76 2000|
|The Physical Object|
|Pagination||vi, 83 p. :|
|Number of Pages||83|
|LC Control Number||00304885|
Introduction. Epilepsy is a long-term disease which requires chronic therapy. The prevalence of epilepsy in India varies from to per population. Neurocysticersosis is one the important reasons for secondary seizures and it is known that in % of neurocysticercosis, seizures are the most common presenting symptom. Amongst the various factors affecting anti-epileptic drug. The majority of the new antiepileptic drugs gained initial FDA approval based on randomized, double-blind, placebo-controlled clinical trials in which the new antiepileptic drug was used as adjunctive treatment. Typically, trials enrolled patients with refractory partial-onset seizures to receive either the study drug or placebo in addition to.
Discuss the spectrum of efficacy, clinical pharmacology, and modes of use for individual antiepileptic drugs Discuss the evaluation of a patient with drug-resistant epilepsy and recognize the role and indications for surgical and nonsurgical options for patients with drug-resistant epilepsy. Mechanisms of action of antiepileptic drugs The therapeutic armamentarium for the treat-ment of seizures has broadened significantly over the past decade . Many of the newer antiepileptic drugs (AEDs) have clinical advan-tages over older, so-called ‘first-generation’ AEDs in that they are more predictable in their.
Study Flashcards On Pharmacology - Exam 2g - Antiepileptic Drugs at Quickly memorize the terms, phrases and much more. makes it easy to get the grade you want! The Frequency and Clinical Features of Hypersensitivity Reactions to Antiepileptic Drugs in Children: A Prospective Study (AEDs) can cause hypersensitivity reactions during childhood. Studies report a wide clinical spectrum of reactions with AED use, ranging from a .
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Get this from a library. Broadening the spectrum of clinical uses of antiepileptic drugs: proceedings of a symposium sponsored by Parke-Davis Pharmaceuticals held in Montreux, Switzerland, 4 June [John M Pellock;].
Author(s): Pellock,John M Title(s): Broadening the spectrum of clinical uses of antiepileptic drugs: proceedings of a symposium sponsored by Parke-Davis Pharmaceuticals held in Montreux, Switzerland, 4 June / edited by J. Pellock. This fully updated book is an authoritative reference guide for the spectrum of diverse clinicians and allied health professionals who prescribe antiepileptic drugs in contemporary clinical practice.
It includes clear information on thirty-five antiepileptic drugs, including newly-approved drug brivaracetam, and is essential for quick reference Cited by: Purpose. The National Centre for Epilepsy in Norway admits patients with refractory epilepsy from the whole country.
The purpose of this study was to investigate how antiepileptic drugs (AEDs) are used at the centre and compare it with the total consumption in the country and international guidelines regarding clinical use of by: has a great section on antiepileptic drugs (AEDs), but I often have been asked for a brief summary document that pulls the information into one package.
This summary represents the opinion of the author, Dr. Robert Fisher, who is an epilepsy specialist, and it is not necessarily the official drug description that can be found in the package insert.
Antiepileptic drugs (AEDs) are widely used as long-term adjunctive therapy or as monotherapy in epilepsy and other indications and consist of a group of drugs that are highly susceptible to interactions. During the last years several new AEDs have been marketed.
Initially, all new AEDs are licensed for add-on therapy for epilepsy patients. The current review summarizes the main antiepileptic drugs available for prescription in the United States as of July One condensed, and one expanded, table of the major properties of 28 AEDs are presented both to assist clinicians in providing care to persons with epilepsy and to facilitate the training of those in health care educational programs.
The armamentarium to treat epilepsy includes today more than twenty drugs. These are classically distinguished as standard, traditional or first generation antiepileptic drugs (AEDs), which include phenobarbital, phenytoin, carbamazepine, valproic acid, ethosuximide and benzodiazepines, and new or second generation AEDs, which are vigabatrin, lamotrigine, felbamate, gabapentin, oxcarbazepine.
• Broadening the spectrum of clinical uses of antiepileptic drugs: proceedings of a symposium sponsored by Parke-Davis Pharmaceuticals held in Montreux, Switzerland, 4 June Author: edited by J.
Pellock; Year: ; London; Lake Forest, IL: Royal Society of Medicine Press, c; ISBN: A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text.
Improving diagnosis and broadening the phenotypes in early-onset seizure and severe developmental delay disorders through gene panel analysis The use of antiepileptic drugs—principles and practice.
Epilepsia Nakagawa E, Fukasawa T, Uchiya S, Hirose S. Clinical spectrum of SCN2A mutations. Brain Dev ; –5. doi/j. Carbamazepine, and the newer but structurally related oxcabazepine and eslicarbazepine acetate, belongs to the dibenzazepine group of antiepileptic drugs, mainly used for patients with focal epilepsy.
effects from the use of antiepileptic drugs (AEDs). Con-sequently, treatment strategies that focus only on seizure reduction are inadequate and ultimately unsuccessful in up to half of the epileptic population.
Due to the com-plexity and multiple facets of the disease, a broader per-spective that addresses the needs of the whole patient is. Fourteen AEDs were used in this cohort: 9 classified as conventional, and 5 as new ().VPA was most frequently used ( and 68 patients in the SCN1A-positive and SCN1A-negative group, respectively).In the SCN1A-positive group, the next most commonly used drugs were phenobarbital (PB, 63), zonisamide (ZNS, 55), bromide (Br, including potassium bromide and sodium.
Learn antiepileptic drugs with free interactive flashcards. Choose from different sets of antiepileptic drugs flashcards on Quizlet. Total destruction of the hematopoietic elements leads to the clinical entity known as aplastic anemia. Aplastic anemia can arise by several mechanisms—immunologic, infectious, constitutional, idiopathic, and physicochemical.
This discussion is limited to chemically mediated aplastic anemia induced by antiepileptic drugs (AEDs). Title: Retigabine: Could it be the Next Broad-Spectrum Antiepileptic Drug. VOLUME: 5 ISSUE: 1 Author(s):Steve S. Chung Affiliation:Department of Neurology; West Thomas Road Suite ; Phoenix, ArizonaUSA.
Abstract: Retigabine is a new anticonvulsant in clinical development, which activates neuronal M-current by opening voltage-gated potassium channels (KCNQ2/3 and.
The thoroughly revised, updated Fifth Edition of this classic is the m ost comprehensive, current, and authoritative reference on all anticon vulsants available today. This edition features detailed profiles of n ewer drugs--including levetiracetam, oxcarbazepine, tiagabine, topiram ate, and zonisamide--and new chapters on use of antiepileptic drugs in children and during pregnancy.
This updated third edition of a successful book is a description of both pharmacokinetic and pharmacodynamic antiepileptic drug (AED) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be coprescribed without undue concern.
h Antiepileptic drugs that are narrow spectrum are much more effective at controlling seizures associated with select syndromes or within a specific category (partial versus generalized).
Other antiepileptic drugs are broad-spectrum agents able to treat both partial and generalized epilepsy. Challenging Concepts in Neurology reviews over twenty difficult presentations in neurology encompassing the wide spectrum of neurological disease.
The cases include unusual emergency presentations such as posterior circulation stroke and non-convulsive status epilepticus, as well as important conditions that are less familiar such as dystonia, viral or autoimmune encephalitis, and.
Over the last few years, preliminary studies have explored the potential efficacy of antiepileptic drugs (AEDs) in controlling tics (Goetz,Steingard et al.,Troung et al., ). AEDs are characterized by multiple mechanisms of action, which can account for their multifaceted spectrum of therapeutic actions.Over the subsequent years, the number of available efficacious antiepileptic drugs has increased and their pattern of clinical use has evolved progressively.
Since the previous version of the present book appeared in there has been continuing gradual, rationally based development in the practice of antiepileptic drug therapy.